Article
Raf-interactome in tuning the complexity and diversity of Raf function.
The FEBS journal - 1 Jan 2015
An Su, Yang Yang, Ward Richard, Liu Ying, Guo Xiao-Xi, Xu Tian-Rui
Abstract excerpt
Raf kinases have been intensely studied subsequent to their discovery 30 years ago. The Ras-Raf-mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-extracellular signal-regulated kinase/mitogen-activated protein kinase (Ras-Raf-MEK-ERK/MAPK) signaling pathway is at the heart of the signaling networks that control many fundamental cellular processes and Raf kinases takes centre stage in...
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