Raf-interactome in tuning the complexity and diversity of Raf function.

doi:10.1111/febs.13113

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Article

Raf-interactome in tuning the complexity and diversity of Raf function.

The FEBS journal - 1 Jan 2015

An Su, Yang Yang, Ward Richard, Liu Ying, Guo Xiao-Xi, Xu Tian-Rui

Abstract excerpt

Raf kinases have been intensely studied subsequent to their discovery 30 years ago. The Ras-Raf-mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-extracellular signal-regulated kinase/mitogen-activated protein kinase (Ras-Raf-MEK-ERK/MAPK) signaling pathway is at the h...

Topics

Animals
Humans
MAP Kinase Signaling System
Mice
Models, Biological
Mutation
Neoplasms
Protein Interaction Maps
raf Kinases

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