Article
Atherosclerosis in aged mice over-expressing the reverse cholesterol transport genes.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Mar 2005
Berti J A, de Faria E C, Oliveira H C F
Abstract excerpt
We determined whether over-expression of one of the three genes involved in reverse cholesterol transport, apolipoprotein (apo) AI, lecithin-cholesterol acyl transferase (LCAT) and cholesteryl ester transfer protein (CETP), or of their combinations influenced the development of diet-induced atherosclerosis. Eight genotypic groups of mice were studied (AI, LCAT, CETP, LCAT/AI, CETP/AI, LCAT/CETP, LCAT/AI/CETP, and...
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