Article
Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI.
Nature - 19 Sept 1991
Rubin E M, Krauss R M, Spangler E A, Verstuyft J G, Clift S M
Abstract excerpt
Epidemiological surveys have identified a strong inverse relationship between the amount in the plasma of high density lipoproteins (HDL), apolipoprotein AI (ApoA-I), the major protein component of HDL, and the risk for atherosclerosis in humans. It is not known if this relationship arises from a direct antiatherogenic effect of these plasma components or if it is the result of other factors also associated with...
Topics
- Animals
- Aorta
- Apolipoprotein A-I
- Apolipoproteins A
- Arteriosclerosis
- Butter
- Cholesterol, Dietary
- Diet, Atherogenic
- Genetic Predisposition to Disease
- Humans
- Lipoproteins, HDL