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Article

Mouse models of atherosclerosis.

Science (New York, N.Y.) - 3 May 1996

Breslow J L

Abstract excerpt

As a species the mouse is highly resistant to atherosclerosis. However, through induced mutations it has been possible to develop lines of mice that are susceptible to this disease. For example, mice that are deficient in apolipoprotein E, a ligand important in lipoprotein clearance, develop atherosclerotic lesions resembling those observed in humans. These lesions are exacerbated when the mice are fed a...

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Identifiers

PMID: 8614828
DOI: 10.1126/science.272.5262.685

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Source receipt: pubmed, retrieved 7 Sept 2026.

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