Article
Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models.
Frontiers in bioscience : a journal and virtual library - 1 Jan 2006
Sarria Alfonso J, Surra Joaquin C, Acin Sergio, Carnicer Ricardo, Navarro Maria A, Arbones-Mainar Jose M, Guillen Natalia, Martinez-Gracia Maria V, Arnal Carmen, Osada Jesus
Abstract excerpt
The generation by genetic engineering of two murine models to investigate atherosclerosis, such as the apoE- and LDLr- deficient mice, is providing an extraordinaire knowledge of the effect of different nutrients on this complex disease. The present revision provides a comprehensive overview of the advances in this field that point to a remarkable complexity. While some controversies over puzzling results could...
Topics
- Alcohol Drinking
- Allergy and Immunology
- Animals
- Antioxidants
- Apolipoproteins E
- Arginine
- Arteriosclerosis
- Ascorbic Acid
- Atherosclerosis
- Cell Proliferation