Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Stochastic modeling of T cell receptor gamma gene rearrangement.

Journal of theoretical biology - 21 May 2005

Sepúlveda Nuno, Boucontet Laurent, Pereira Pablo, Carneiro Jorge

Abstract excerpt

The mechanisms controlling the recombination process of the gamma genes that encode the gamma chain of the antigen receptor of the gammadelta T lymphocytes are unclear. Based on experimental data on the recombination status of the two major TCR gamma genes expressed in V(gamma)4+ and V(gamma)1+ thymocytes, we tested the plausibility of three possible rearrangement mechanisms: (1) a time window mechanism according...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Feedback, Physiological
Share to Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Markov Chains

Share to Models, Genetic

Share to Receptors, Antigen, T-Cell, gamma-delta

Share to T-Lymphocyte Subsets

Share to Thymus Gland

Source

Identifiers

PMID: 15757675
DOI: 10.1016/j.jtbi.2004.11.018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Stochastic modeling of T cell receptor gamma gene rearrangement.PMID 15757675Read ↗

TCR beta allelic exclusion in dynamical models of V(D)J recombination based on allele independence.Semantic proximity Read ↗

Genetic organization of the human T cell receptor gamma locus.Semantic proximity Read ↗

[T-lymphocyte receptor genes: genome organization and genetic mechanisms of repertoire diversity].Semantic proximity Read ↗

Models for antigen receptor gene rearrangement. II. Multiple rearrangement in the TCR: allelic exclusion or inclusion?Semantic proximity Read ↗

Allelic exclusion at the TCR delta locus and commitment to gamma delta lineage: different modalities apply to distinct human gamma delta subsets.Semantic proximity Read ↗

Dynamic regulation of antigen receptor gene assembly.Semantic proximity Read ↗

Mechanisms controlling termination of V-J recombination at the TCRgamma locus: implications for allelic and isotypic exclusion of TCRgamma chains.Semantic proximity Read ↗

Long-Range Control of V(D)J Recombination & Allelic Exclusion: Modeling Views.Semantic proximity Read ↗

A model for TCR gene segment use.Semantic proximity Read ↗

Models for antigen receptor gene rearrangement. I. Biased receptor editing in B cells: implications for allelic exclusion.Semantic proximity Read ↗

Models for antigen receptor gene rearrangement: CDR3 lengthSemantic proximity Read ↗

Mechanisms that control antigen receptor variable region gene assembly.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.