Article
Models for antigen receptor gene rearrangement. II. Multiple rearrangement in the TCR: allelic exclusion or inclusion?
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1999
Piper H, Litwin S, Mehr R
Abstract excerpt
This series of papers addresses the effects of continuous Ag receptor gene rearrangement in lymphocytes on allelic exclusion. The previous paper discussed light chain gene rearrangement and receptor editing in B cells, and showed that these processes are ordered on three different levels. This order, combined with the constraints imposed by a strong negative selection, was shown to lead to effective allelic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
