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Article

Airway fibroblasts exhibit a synthetic phenotype in severe asthma.

The Journal of allergy and clinical immunology - 1 Mar 2005

Lewis Christina C, Chu Hong Wei, Westcott Jay Y, Tucker Alan, Langmack Esther L, Sutherland E Rand, Kraft Monica

Abstract excerpt

BACKGROUND: Platelet-derived growth factor (PDGF) may have a significant role in airway remodeling in asthma, because it is a powerful inductor of many airway fibroblast activities such as collagen synthesis. OBJECTIVE: To determine whether PDGF is a significant contributor to airway remodeling in patients with asthma by enhancing airway fibroblast procollagen I expression. METHODS: Six normal controls without...

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Source

Identifiers

PMID: 15753901
DOI: 10.1016/j.jaci.2004.11.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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