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Article

Fibroblast‐derived exosomes promote epithelial cell proliferation through TGF ‐β2 signalling pathway in severe asthma

26 Jun 2017

Abstract excerpt

BACKGROUND: Bronchial fibroblasts play a key role in airway remodelling in asthma. They regulate epithelial cell functions such as proliferation through growth factors, cytokines, chemokines and exosomes. The role of exosomes in the communication between epithelial cells and fibroblasts by vehiculing these mediators in asthma remains to be determined. OBJECTIVE: To evaluate the role of exosomes released by...

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Share to Asthma and respiratory diseases
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PMID: 28649804
DOI: 10.1111/all.13234

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