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Article

Regional fibroblast heterogeneity in the lung: implications for remodeling.

American journal of respiratory and critical care medicine - 1 Jun 2006

Kotaru Chakradhar, Schoonover Kathryn J, Trudeau John B, Huynh Mai-Lan, Zhou XiuXia, Hu Haizhen, Wenzel Sally E

Abstract excerpt

RATIONALE: Excessive deposition of extracellular matrix occurs in proximal airways of individuals with asthma, but fibrosis in distal lung has not been observed. Whether differing fibrotic capacities of fibroblasts from these two regions contribute to this variability is unknown. OBJECTIVES: We compared morphologic and functional characteristics of fibroblasts isolated from proximal airways and distal lung...

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Identifiers

PMID: 16543551
DOI: 10.1164/rccm.200508-1218OC
PMCID: PMC2662967

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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