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Article

Fibroblast-to-myofibroblast transition in bronchial asthma

12 Aug 2018

Abstract excerpt

Bronchial asthma is a chronic inflammatory disease in which bronchial wall remodelling plays a significant role. This phenomenon is related to enhanced proliferation of airway smooth muscle cells, elevated extracellular matrix protein secretion and an increased number of myofibroblasts. Phenotypic fibroblast-to-myofibroblast transition represents one of the primary mechanisms by which myofibroblasts arise in...

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PMID: 30101406
DOI: 10.1007/s00018-018-2899-4

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