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Article

Functional consequences of human airway smooth muscle phenotype plasticity.

British journal of pharmacology - 1 May 2012

Dekkers Bart G J, Bos I Sophie T, Zaagsma Johan, Meurs Herman

Abstract excerpt

BACKGROUND AND PURPOSE: Airway smooth muscle (ASM) phenotype plasticity, characterized by reversible switching between contractile and proliferative phenotypes, is considered to contribute to increased ASM mass and airway hyper-responsiveness in asthma. Further, increased expression of collagen I has been observed within the ASM bundle of asthmatics. Previously, we showed that exposure of intact bovine tracheal...

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Identifiers

PMID: 22053853
DOI: 10.1111/j.1476-5381.2011.01773.x
PMCID: PMC3415660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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