Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in SPINK5 are not associated with asthma in a Dutch population.

The Journal of allergy and clinical immunology - 1 Mar 2005

Jongepier Hajo, Koppelman Gerard H, Nolte Ilja M, Bruinenberg Marcel, Bleecker Eugene R, Meyers Deborah A, te Meerman Gerard J, Postma Dirkje S

Abstract excerpt

BACKGROUND: Asthma and allergic phenotypes are complex genetic diseases with known linkage to chromosome 5q. This region has many candidate genes, including serine protease inhibitor Kazal type 5 (SPINK5), which has been associated with asthma and atopic dermatitis in family-based studies of children with atopic dermatitis. OBJECTIVE: We sought to investigate whether single nucleotide polymorphisms in SPINK5 are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dermatitis, Atopic

Share to Gene Frequency

Share to Netherlands

Share to Polymerase Chain Reaction

Share to Proteinase Inhibitory Proteins, Secretory

Share to Serine Peptidase Inhibitor Kazal-Type 5

Source

Identifiers

PMID: 15753894
DOI: 10.1016/j.jaci.2004.12.013

Genes

SPINK5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in SPINK5 are not associated with asthma in a Dutch population.PMID 15753894Read ↗

Association between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sample.Semantic proximity Read ↗

Association between polymorphisms in the SPINK5 gene and atopic dermatitis in the Japanese.Semantic proximity Read ↗

A functional polymorphism in the SPINK5 gene is associated with asthma in a Chinese Han Population.Semantic proximity Read ↗

Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma.Semantic proximity Read ↗

Gene polymorphism in Netherton and common atopic disease.Semantic proximity Read ↗

Hint for association of single nucleotide polymorphisms and haplotype in SPINK5 gene with atopic dermatitis in Koreans.Semantic proximity Read ↗

Association of SPINK5 gene polymorphisms with atopic dermatitis in Northeast China.Semantic proximity Read ↗

Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk.Semantic proximity Read ↗

Analysis of SPINK 5, KLK 7 and FLG genotypes in a French atopic dermatitis cohort.Semantic proximity Read ↗

A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins.Semantic proximity Read ↗

Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome.Semantic proximity Read ↗

Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthmaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.