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Article

Analysis of SPINK 5, KLK 7 and FLG genotypes in a French atopic dermatitis cohort.

Acta dermato-venereologica - 1 Jan 2007

Hubiche Thomas, Ged Cécile, Benard Antoine, Léauté-Labrèze Christine, McElreavey Ken, de Verneuil Hubert, Taïeb Alain, Boralevi Franck

Abstract excerpt

The role of a genetically impaired epidermal barrier as a major predisposing factor in the pathogenesis of atopic disorders is currently under closer investigation. Variants on three candidate genes (SPINK5, KLK7 and FLG) have been associated with atopic dermatitis. A functional relevance has already been established for filaggrin variants, but not for SPINK5 and KLK7 polymorphisms. The objectives of this study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proteinase Inhibitory Proteins, Secretory

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Serine Peptidase Inhibitor Kazal-Type 5

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Source

Identifiers

PMID: 17989887
DOI: 10.2340/00015555-0329

Genes

SPINK5
KLK7
FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of SPINK 5, KLK 7 and FLG genotypes in a French atopic dermatitis cohort.PMID 17989887Read ↗

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