Article
Evolution of relative synonymous codon usage in Human Immunodeficiency Virus type-1.
Journal of bioinformatics and computational biology - 1 Feb 2005
Meintjes Peter L, Rodrigo Allen G
Abstract excerpt
Mutation in Human Immunodeficiency Virus type-1 (HIV-1) is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate of approximately 1% per year and can frequently spend a long time in the host (approximately 10 years). The relative synonymous codon usage (RSCU) in HIV-1 is known to be different from that of the...
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