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Article

Adaptation to different human populations by HIV-1 revealed by codon-based analyses.

PLoS computational biology - 23 Jun 2006

Pond Sergei L Kosakovsky, Frost Simon D W, Grossman Zehava, Gravenor Michael B, Richman Douglas D, Brown Andrew J Leigh

Abstract excerpt

Several codon-based methods are available for detecting adaptive evolution in protein-coding sequences, but to date none specifically identify sites that are selected differentially in two populations, although such comparisons between populations have been historically useful in identifying the action of natural selection. We have developed two fixed effects maximum likelihood methods: one for identifying codon...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16789820
DOI: 10.1371/journal.pcbi.0020062
PMCID: PMC1480537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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