Article
Codon usage of HIV regulatory genes is not determined by nucleotide composition.
Archives of virology - 1 Feb 2018
Phakaratsakul Supinya, Sirihongthong Thanyaporn, Boonarkart Chompunuch, Suptawiwat Ornpreya, Auewarakul Prasert
Abstract excerpt
Codon usage bias can be a result of either mutational bias or selection for translational efficiency and/or accuracy. Previous data has suggested that nucleotide composition constraint was the main determinant of HIV codon usage, and that nucleotide composition and codon usage were different between the regulatory genes, tat and rev, and other viral genes. It is not clear whether translational selection...
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