Article
Intra-host evolutionary rates in HIV-1C env and gag during primary infection.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2013
Novitsky Vlad, Wang Rui, Rossenkhan Raabya, Moyo Sikhulile, Essex M
Abstract excerpt
BACKGROUND: HIV-1 nucleotide substitution rates are central for understanding the evolution of HIV-1. Their accurate estimation is critical for analysis of viral dynamics, identification of divergence time of HIV variants, inference of HIV transmission clusters, and modeling of viral evolution. METHODS: Intra-patient nucleotide substitution rates in HIV-1C gag and env gp120 V1C5 were analyzed in a longitudinal...
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