Article
Keratin-containing inclusions affect cell morphology and distribution of cytosolic cellular components.
Experimental cell research - 1 Apr 2005
Hanada Shinichiro, Harada Masaru, Kumemura Hiroto, Omary M Bishr, Kawaguchi Takumi, Taniguchi Eitaro, Koga Hironori, Yoshida Takafumi, Maeyama Michiko, Baba Shinji, Ueno Takato, Sata Michio
Abstract excerpt
Many neurodegenerative diseases are characterized by the presence of protein aggregates bundled with intermediate filaments (IFs) and similar structures, known as Mallory bodies (MBs), are observed in various liver diseases. IFs are anchored at desmosomes and hemidesmosomes, however, interactions with other intercellular junctions have not been determined. We investigated the effect of IF inclusions on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
