Article
The keratin cytoskeleton in liver diseases.
The Journal of pathology - 1 Nov 2004
Zatloukal Kurt, Stumptner Conny, Fuchsbichler Andrea, Fickert Peter, Lackner Carolin, Trauner Michael, Denk Helmut
Abstract excerpt
The keratin intermediate filament (IF) cytoskeleton of hepatocytes has continuously gained medical relevance over the last two decades. Originally it was mainly recognized as a differentiation marker for diagnostic purposes in pathology. However, keratin IFs were soon identified as major cellular structures to be affected in a variety of chronic liver diseases, such as alcoholic and non-alcoholic steatohepatitis...
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