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Article

Simple Epithelial Keratins.

Methods in enzymology - 1 Jan 2016

Strnad Pavel, Guldiken Nurdan, Helenius Terhi O, Misiorek Julia O, Nyström Joel H, Lähdeniemi Iris A K, Silvander Jonas S G, Kuscuoglu Deniz, Toivola Diana M

Abstract excerpt

Simple epithelial keratins (SEKs) are the cytoplasmic intermediate filament proteins of single-layered and glandular epithelial cells as found in the liver, pancreas, intestine, and lung. SEKs have broad cytoprotective functions, which are facilitated by dynamic posttranslational modifications and interaction with associated proteins. SEK filaments are composed of obligate heteropolymers of type II (K7, K8) and...

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PMID: 26795477
DOI: 10.1016/bs.mie.2015.08.004

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