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Article

Association studies of MMP-9 in Parkinson's disease and amyotrophic lateral sclerosis.

PloS one - 1 Jan 2013

He Xianghua, Zhang Lifang, Yao Xiaoli, Hu Jing, Yu Lihua, Jia Hua, An Ran, Liu Zhuolin, Xu Yanming

Abstract excerpt

Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) share several clinical and neuropathologic features, and studies suggest that several gene mutations and polymorphisms are involved in both conditions. Matrix metalloproteinase-9 (MMP-9) is implicated in the pathogenesis of PD and ALS, and the C(-1562)T polymorphism in the MMP-9 gene leads to higher promoter activity. We therefore investigated...

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Identifiers

PMID: 24040066
DOI: 10.1371/journal.pone.0073777
PMCID: PMC3767588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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