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Article

Monitoring in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm infection model.

The Journal of antimicrobial chemotherapy - 1 Apr 2005

Yu Jun, Wu Jenny, Francis Kevin P, Purchio Tony F, Kadurugamuwa Jagath L

Abstract excerpt

OBJECTIVES: To investigate in vivo fitness of rifampicin-resistant Staphylococcus aureus mutants in a mouse biofilm model using bioluminescence imaging. MATERIALS AND METHODS: S. aureus was engineered with a luciferase operon to emit bioluminescence that can be detected in vivo using an IVIS imaging system. Two rifampicin-resistant strains of S. aureus that were previously isolated from animals undergoing...

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Identifiers

PMID: 15743898
DOI: 10.1093/jac/dki053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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