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Stably Luminescent Staphylococcus aureus Clinical Strains for Use in Bioluminescent Imaging

12 Mar 2013

Abstract excerpt

In vivo bioluminescent imaging permits the visualization of bacteria in live animals, allowing researchers to monitor, both temporally and spatially, the progression of infection in each animal. We sought to engineer stably luminescent clinical strains of Staphylococcus aureus, with the goal of using such strains in mouse models. The gram-positive shuttle vector pMAD was used as the backbone for an integration...

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PMID: 23555002
DOI: 10.1371/journal.pone.0059232

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