Article
Construction and Use of Staphylococcus aureus Strains to Study Within-Host Infection Dynamics.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
McVicker Gareth, Prajsnar Tomasz K, Foster Simon J
Abstract excerpt
The study of the dynamics that occur during the course of a bacterial infection has been attempted using several methods. Here we discuss the construction of a set of antibiotic-resistant, otherwise-isogenic Staphylococcus aureus strains that can be used to observe the progress of systemic disease in a mouse model at various time-points postinfection. The strains can likewise be used to study the progression of...
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