Article
RNA polymerase B subunit gene mutations in biofilm-embedded methicillin-resistant Staphylococcus aureus following rifampin treatment.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Jun 2016
Tang Hung-Jen, Lai Chih-Cheng, Hsueh Po-Ren, Chen Chi-Chung, Wu Kuan-Ying, Lin Yi-Chung, Zhang Chun-Cheng, Weng Tzu-Chieh, Chiu Yu-Hsin, Toh Han-Siong, Chiang Shyh-Ren, Yu Wen-Liang, Ko Wen-Chien, Chuang Yin-Ching
Abstract excerpt
BACKGROUND/PURPOSE: This study was conducted to compare the mutation rates of different rpoB sites and rifampin minimum inhibitory concentration (MIC) changes prior to and after rifampin therapy for biofilm-embedded methicillin-resistant Staphylococcus aureus (MRSA) isolates. METHODS: The screening of rifampin-resistant MRSA isolates, from the biofilm at Day 5 with or without exposure to the susceptible...
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