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Article

Evaluating the Targeting of a Staphylococcus-aureus-Infected Implant with a Radiolabeled Antibody In Vivo

22 Feb 2023

Abstract excerpt

Implant infections caused by Staphylococcus aureus are difficult to treat due to biofilm formation, which complicates surgical and antibiotic treatment. We introduce an alternative approach using monoclonal antibodies (mAbs) targeting S. aureus and provide evidence of the specificity and biodistribution of S.-aureus-targeting antibodies in a mouse implant infection model. The monoclonal antibody 4497-IgG1...

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Infective Endocarditis Diagnosis and Management
Orthopaedic implants and arthroplasty
Orthopedic Infections and Treatments

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36901805
DOI: 10.3390/ijms24054374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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