Article
Association of C-reactive protein with blood pressure and hypertension: life course confounding and mendelian randomization tests of causality.
Arteriosclerosis, thrombosis, and vascular biology - 1 May 2005
Davey Smith George, Lawlor Debbie A, Harbord Roger, Timpson Nic, Rumley Ann, Lowe Gordon D O, Day Ian N M, Ebrahim Shah
Abstract excerpt
BACKGROUND: C-reactive protein (CRP) has repeatedly been associated with blood pressure and prevalent and incident hypertension, but whether a causal link exists is uncertain. METHODS AND RESULTS: We assessed the cross-sectional relations of CRP to systolic blood pressure, pulse pressure, and prevalent hypertension in a representative sample of >3500 British women aged 60 to 79 years. For both outcomes,...
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