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Article

Association of high sensitive C-reactive protein with coronary heart disease: a Mendelian randomization study.

BMC medical genetics - 6 Nov 2019

Zhuang Qian, Shen Chong, Chen Yanchun, Zhao Xianghai, Wei Pengfei, Sun Junxiang, Ji Yanni, Chen Xiaotian, Yang Song

Abstract excerpt

OBJECTIVES: Whether high sensitivity C-reactive protein (hs-CRP) has a causal effect on coronary heart disease (CHD) is unclear. This study investigated the causal effect of hs-CRP on CHD risk using Mendelian Randomization (MR) analysis. METHODS: A total of 3802 subjects were recruited in the follow-up study. Linear regression model was used to evaluate the relationship between CRP polymorphisms and hs-CRP....

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Identifiers

PMID: 31694563
DOI: 10.1186/s12881-019-0910-z
PMCID: PMC6836320

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