Article
The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study.
Clinical science (London, England : 1979) - 1 Apr 2011
Bolton Charlotte E, Schumacher Wiebke, Cockcroft John R, Timpson Nicholas J, Smith George Davey, Gallacher John, Rumley Anne, Lowe Gordon D, Ebrahim Shah, Shale Dennis J, Ben-Shlomo Yoav
Abstract excerpt
Systemic CRP (C-reactive protein) has been associated with impaired lung function. A causal relationship would increase the value of CRP as both a diagnostic and therapeutic tool. We assessed the association between lung function parameters, circulating CRP and CRP polymorphisms using Mendelian randomization in efforts to attribute causality to known associations. Spirometric parameters of FEV1 (forced expiratory...
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