Article
Pairs of Vp1 cysteine residues essential for simian virus 40 infection.
Journal of virology - 1 Mar 2005
Li Peggy P, Nakanishi Akira, Fontanes Vanessa, Kasamatsu Harumi
Abstract excerpt
Transient disulfide bonding occurs during the intracellular folding and pentamerization of simian virus 40 (SV40) major capsid protein Vp1 (P. P. Li, A. Nakanishi, S. W. Clark, and H. Kasamatsu, Proc. Natl. Acad. Sci. USA 99:1353-1358, 2002). We investigated the requirement for Vp1 cysteine pairs during SV40 infection. Our analysis identified three Vp1 double-cysteine mutant combinations that abolished viability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
