Article
Translocation and surface expression of lipidated serogroup B capsular Polysaccharide in Neisseria meningitidis.
Infection and immunity - 1 Mar 2005
Tzeng Yih-Ling, Datta Anup K, Strole Cristy A, Lobritz Michael A, Carlson Russell W, Stephens David S
Abstract excerpt
The capsule of N. meningitidis serogroup B, (alpha2-->8)-linked polysialic acid and the capsules of other meningococcal serogroups and of other gram-negative bacterial pathogens are anchored in the outer membrane through a 1,2-diacylglycerol moiety. Previous work on the meningococcal cps complex in Escherichia coli K-12 indicated that deletion of genes designated lipA and lipB caused intracellular accumulation of...
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