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Regulation of capsule inNeisseria meningitidis

19 Jun 2015

Abstract excerpt

Neisseria meningitidis, a devastating pathogen exclusive to humans, expresses capsular polysaccharides that are the major meningococcal virulence determinants and the basis for successful meningococcal vaccines. With rare exceptions, the expression of capsule (serogroups A, B, C, W, X, Y) is required for systemic invasive meningococcal disease. Changes in capsule expression or structure (e.g. hypo- or...

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PMID: 26089023
DOI: 10.3109/1040841x.2015.1022507

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