Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Involvement of Neisseria meningitidis lipoprotein GNA2091 in the assembly of a subset of outer membrane proteins.

The Journal of biological chemistry - 30 May 2014

Bos Martine P, Grijpstra Jan, Tommassen-van Boxtel Ria, Tommassen Jan

Abstract excerpt

GNA2091 of Neisseria meningitidis is a lipoprotein of unknown function that is included in the novel 4CMenB vaccine. Here, we investigated the biological function and the subcellular localization of the protein. We demonstrate that GNA2091 functions in the assembly of outer membrane proteins (OMPs) because its absence resulted in the accumulation of misassembled OMPs. Cell fractionation and protease accessibility...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Outer Membrane Proteins
Share to Bacterial Vaccines

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Gene Deletion

Share to Lipoproteins

Share to Mutagenesis

Share to Neisseria meningitidis, Serogroup B

Share to Porins

Source

Open in PubMed Open full text

Identifiers

PMID: 24755216
DOI: 10.1074/jbc.M113.539510
PMCID: PMC4140915

Genes

OMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of Neisseria meningitidis lipoprotein GNA2091 in the assembly of a subset of outer membrane proteins.PMID 24755216Read ↗

Towards the Immunoproteome of Neisseria meningitidisSemantic proximity Read ↗

Induction of immune responses by purified outer membrane protein complexes from Neisseria meningitidis.Semantic proximity Read ↗

Proteomic analysis of outer membranes and vesicles from wild-type serogroup B Neisseria meningitidis and a lipopolysaccharide-deficient mutant.Semantic proximity Read ↗

Vaccination against <i>Neisseria meningitidis</i> Using Three Variants of the Lipoprotein GNA1870Semantic proximity Read ↗

Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process.Semantic proximity Read ↗

The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance.Semantic proximity Read ↗

OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humansSemantic proximity Read ↗

Biological Functions of the Secretome of Neisseria meningitidisSemantic proximity Read ↗

Immunoproteomic identification of the hypothetical protein NMB1468 as a novel lipoprotein ubiquitous in <b><i>Neisseria meningitidis</i></b> with vaccine potentialSemantic proximity Read ↗

Comparative Proteome Analysis of Spontaneous Outer Membrane Vesicles and Purified Outer Membranes of Neisseria meningitidisSemantic proximity Read ↗

Structure of the C-terminal Domain of Neisseria Heparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine against Neisseria meningitidisSemantic proximity Read ↗

Function of Neisserial Outer Membrane Phospholipase A in Autolysis and Assessment of Its Vaccine PotentialSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.