Article
Lipooligosaccharide structure contributes to multiple steps in the virulence of Neisseria meningitidis.
Infection and immunity - 1 Feb 2006
Plant Laura, Sundqvist Johanna, Zughaier Susu, Lövkvist Lena, Stephens David S, Jonsson Ann-Beth
Abstract excerpt
Lipooligosaccharide (LOS) of Neisseria meningitidis has been implicated in meningococcal interaction with host epithelial cells and is a major factor contributing to the human proinflammatory response to meningococci. LOS mutants of the encapsulated N. meningitidis serogroup B strain NMB were used to further determine the importance of the LOS structure in in vitro adherence and invasion of human pharyngeal...
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