Article
Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum.
Development (Cambridge, England) - 1 Jul 2011
Yu Tian, Yaguchi Yuichiro, Echevarria Diego, Martinez Salvador, Basson M Albert
Abstract excerpt
Fibroblast growth factors (FGFs) and regulators of the FGF signalling pathway are expressed in several cell types within the cerebellum throughout its development. Although much is known about the function of this pathway during the establishment of the cerebellar territory during early embryogenesis, the role of this pathway during later developmental stages is still poorly understood. Here, we investigated the...
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