Article
Impact of genetic variability in nicotinic acetylcholine receptors on nicotine addiction and smoking cessation treatment.
Current medicinal chemistry - 1 Jan 2011
Russo P, Cesario A, Rutella S, Veronesi G, Spaggiari L, Galetta D, Margaritora S, Granone P, Greenberg D S
Abstract excerpt
Nicotine dependence (ND) is one of the world's leading causes of preventable death. Nicotine addiction and other forms of drug addiction continue to be significant public health problems in the world. Evidence for a genetic influence on smoking behaviour and ND has prompted a search for susceptibility genes. Evidence has recently accumulated that single nucleotide polymorphisms (SNPs) in the genetic region...
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