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Article

Expression of the human FUSED protein in Drosophila.

Development genes and evolution - 1 May 2005

Daoud Fatma, Blanchet-Tournier Marie-Françoise

Abstract excerpt

The Drosophila segment polarity gene fused, which encodes a serine threonine kinase, is required to transmit the Hedgehog (Hh) signal in imaginal discs. To explore the functional homology between the human protein FUSED (hFU) and the Drosophila protein fused (dFu), we have subjected hFU to a precise and well-defined Hh signalling assay of Drosophila wing development. In the wildtype, hFU affects the expression of...

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Identifiers

PMID: 15726444
DOI: 10.1007/s00427-005-0469-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of the human FUSED protein in Drosophila.PMID 15726444Read ↗

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The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment.Semantic proximity Read ↗

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Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide.Semantic proximity Read ↗

A large disordered region confers a wide spanning volume to vertebrate Suppressor of Fused as shown in a trans-species solution studySemantic proximity Read ↗

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