Article
Functional domains of fused, a serine-threonine kinase required for signaling in Drosophila.
Genetics - 1 Apr 1996
Thérond P, Alves G, Limbourg-Bouchon B, Tricoire H, Guillemet E, Brissard-Zahraoui J, Lamour-Isnard C, Busson D
Abstract excerpt
fused (fu) is a segment-polarity gene encoding a putative serine-threonine kinase. In a wild-type context, all fu mutations display the same set of phenotypes. Nevertheless, mutations of the Suppressor of fused [Su(fu)] gene define three classes of alleles (fuO, fuI, fuII). Here, we report the molecular analysis of known fu mutations and the generation of new alleles by in vitro mutagenesis. We show that the...
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