Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.

Genetics - 1 Dec 1993

Préat T, Thérond P, Limbourg-Bouchon B, Pham A, Tricoire H, Busson D, Lamour-Isnard C

Abstract excerpt

fused (fu) is a segment polarity gene that encodes a putative serine/threonine kinase. A complete suppressor of the embryonic and adult phenotypes of fu mutants, Suppressor of fused (Su(fu)), was previously described. The amorphic Su(fu) mutation is viable and displays no phenotype by itself. We...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
DNA
DNA Primers
Drosophila Proteins
Drosophila melanogaster
Female
Gene Expression
Genes, Recessive
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Phenotype

Protein Serine-Threonine Kinases

Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 8307322
DOI: 10.1093/genetics/135.4.1047
PMCID: PMC1205737

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8307322-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.PMID 8307322Read ↗

Functional domains of fused, a serine-threonine kinase required for signaling in Drosophila.Semantic proximity Read ↗

The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment.Semantic proximity Read ↗

Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster.Semantic proximity Read ↗

Interactions between fused, a segment-polarity gene in Drosophila, and other segmentation genes.Semantic proximity Read ↗

Molecular organisation and expression pattern of the segment polarity gene fused of Drosophila melanogaster.Semantic proximity Read ↗

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila.Semantic proximity Read ↗

The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells.Semantic proximity Read ↗

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.Semantic proximity Read ↗

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development.Semantic proximity Read ↗

Genomic organization and embryonic expression of Suppressor of Fused, a candidate gene for the split-hand/split-foot malformation type 3.Semantic proximity Read ↗

Functional dissection of the paired segmentation gene in Drosophila embryos.Semantic proximity Read ↗

Expression of the human FUSED protein in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.