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Article

Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.

Genetics - 1 Dec 1993

Préat T, Thérond P, Limbourg-Bouchon B, Pham A, Tricoire H, Busson D, Lamour-Isnard C

Abstract excerpt

fused (fu) is a segment polarity gene that encodes a putative serine/threonine kinase. A complete suppressor of the embryonic and adult phenotypes of fu mutants, Suppressor of fused (Su(fu)), was previously described. The amorphic Su(fu) mutation is viable and displays no phenotype by itself. We have used this suppressor as a tool to perform a genetic dissection of the fu gene. Analysis of the interaction between...

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Identifiers

PMID: 8307322
DOI: 10.1093/genetics/135.4.1047
PMCID: PMC1205737

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Segmental polarity in Drosophila melanogaster: genetic dissection of fused in a Suppressor of fused background reveals interaction with costal-2.PMID 8307322Read ↗

Functional domains of fused, a serine-threonine kinase required for signaling in Drosophila.Semantic proximity Read ↗

The Suppressor of fused gene encodes a novel PEST protein involved in Drosophila segment polarity establishment.Semantic proximity Read ↗

Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster.Semantic proximity Read ↗

Interactions between fused, a segment-polarity gene in Drosophila, and other segmentation genes.Semantic proximity Read ↗

Molecular organisation and expression pattern of the segment polarity gene fused of Drosophila melanogaster.Semantic proximity Read ↗

A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila.Semantic proximity Read ↗

The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells.Semantic proximity Read ↗

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.Semantic proximity Read ↗

Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development.Semantic proximity Read ↗

Genomic organization and embryonic expression of Suppressor of Fused, a candidate gene for the split-hand/split-foot malformation type 3.Semantic proximity Read ↗

Functional dissection of the paired segmentation gene in Drosophila embryos.Semantic proximity Read ↗

Expression of the human FUSED protein in Drosophila.Semantic proximity Read ↗

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