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Article

Genetic variation and dynamics of hepatitis C virus replicons in long-term cell culture.

The Journal of general virology - 1 Mar 2005

Kato Nobuyuki, Nakamura Takashi, Dansako Hiromichi, Namba Katsuyuki, Abe Ken-Ichi, Nozaki Akito, Naka Kazuhito, Ikeda Masanori, Shimotohno Kunitada

Abstract excerpt

Hepatitis C virus (HCV) genomic sequences are known to vary widely among HCV strains, but to date there have been few reports on the genetic variations and dynamics of HCV in an experimental system of HCV replication. In this study, a genetic analysis of HCV replicons obtained in long-term culture of two HCV replicon cells (50-1 and 1B-2R1), which were established from two HCV strains, 1B-1 and 1B-2,...

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Source

Identifiers

PMID: 15722525
DOI: 10.1099/vir.0.80479-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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