Article
Evolution of cell culture systems for HCV.
Antiviral therapy - 1 Jan 2013
Taylor Deborah R
Abstract excerpt
Many challenges exist for the study of HCV in the laboratory. Therapy using interferon (IFN) is expensive, not well tolerated and ineffective for many patients. HCV research has been hampered by the lack of a robust tissue culture system, but recent advances have made virus growth in culture possible. Cell culture systems using genetically engineered viruses have been reviewed extensively, but here we review...
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