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Article

The adducin saga: pleiotropic genomic targets for precision medicine in human hypertension-vascular, renal, and cognitive diseases.

Physiological genomics - 1 Feb 2022

Gonzalez-Fernandez Ezekiel, Fan Letao, Wang Shaoxun, Liu Yedan, Gao Wenjun, Thomas Kirby N, Fan Fan, Roman Richard J

Abstract excerpt

Hypertension is a leading risk factor for stroke, heart disease, chronic kidney disease, vascular cognitive impairment, and Alzheimer's disease. Previous genetic studies have nominated hundreds of genes linked to hypertension, and renal and cognitive diseases. Some have been advanced as candidate genes by showing that they can alter blood pressure or renal and cerebral vascular function in knockout animals;...

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Identifiers

PMID: 34859687
DOI: 10.1152/physiolgenomics.00119.2021
PMCID: PMC8799388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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