Alpha-adducin 1 (rs4961) gene and its expression associated with sodium sensitivity in hypertensive patients: a cohort study in the western Ukrainian population.

doi:10.2478/enr-2024-0023

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Article

Alpha-adducin 1 (rs4961) gene and its expression associated with sodium sensitivity in hypertensive patients: a cohort study in the western Ukrainian population.

Endocrine regulations - 1 Jan 2024

Sydorchuk Larysa, Lytvyn Bogdan, Sydorchuk Andrii, Yarynych Yulia, Daruvuri Sai Praveen, Semenenko Svitlana, Hoshovska Alisa, Sydorchuk Ruslan, Biryuk Igor

Abstract excerpt

Objective. The aim of this study was to evaluate the association of the α-adducin-1 gene (ADD1) (Gly460Trp [rs4961]) polymorphism and its expression in association with renal dysfunction and sodium sensitivity in hypertensive patients in western Ukrainian population. Methods. One-hundred patients with essential arterial hypertension (EAH) and hypertensive-mediated target organ damage (stage 2), moderate, high,...

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PMID: 39352780
DOI: 10.2478/enr-2024-0023

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