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Article

Relationship between ADD1 Gly460Trp gene polymorphism and essential hypertension in Madeira Island.

Medicine - 1 Oct 2017

Sousa Ana Célia, Palma Dos Reis Roberto, Pereira Andreia, Borges Sofia, Freitas Ana Isabel, Guerra Graça, Góis Teresa, Rodrigues Mariana, Henriques Eva, Freitas Sónia, Ornelas Ilídio, Pereira Décio, Brehm António, Mendonça Maria Isabel

Abstract excerpt

Essential hypertension (EH) is a complex disease in which physiological, environmental, and genetic factors are involved in its genesis. The genetic variant of the alpha-adducin gene (ADD1) has been described as a risk factor for EH, but with controversial results.The objective of this study was to evaluate the association of ADD1 (Gly460Trp) gene polymorphism with the EH risk in a population from Madeira...

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Identifiers

PMID: 29049185
DOI: 10.1097/MD.0000000000007861
PMCID: PMC5662351

Genes

ADD1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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