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Article

Generality of the structurally constrained protein evolution model: assessment on representatives of the four main fold classes.

Gene - 17 Jan 2005

Parisi Gustavo, Echave Julián

Abstract excerpt

The Structurally Constrained Protein Evolution (SCPE) model simulates protein evolution by introducing random mutations into the evolving sequences and selecting them against too much structural perturbation. Given a single protein structure, the SCPE model can be used to obtain a whole set of site-dependent amino acid substitution matrices. The set of SCPE substitution matrices for a given protein family can be...

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Identifiers

PMID: 15716088
DOI: 10.1016/j.gene.2004.11.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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