Article
Impact of hepatitis C virus heterogeneity on interferon sensitivity: an overview.
World journal of gastroenterology - 28 Jun 2014
El-Shamy Ahmed, Hotta Hak
Abstract excerpt
Hepatitis C virus (HCV) is a major cause of liver disease worldwide. HCV is able to evade host defense mechanisms, including both innate and acquired immune responses, to establish persistent infection, which results in a broad spectrum of pathogenicity, such as lipid and glucose metabolism disorders and hepatocellular carcinoma development. The HCV genome is characterized by a high degree of genetic diversity,...
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