Aberrantly Methylated <i>CDKN2A</i>, <i>MGMT</i>, and <i>MLH1</i> in Colon Polyps and in Fecal DNA from Patients with Colorectal Polyps

Abstract excerpt

Colon cancer is the third leading cause of cancer-related death in the United States, affecting approximately 147,000 people each year. Most colon cancers arise from benign neoplasms and evolve into adenocarcinomas through a stepwise histologic progression sequence that starts from adenomas or hyperplastic polyps/serrated adenomas. Genetic alterations and, more recently, epigenetic alterations have been...

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