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DNA Methylation Patterns as Noninvasive Biomarkers and Targets of Epigenetic Therapies in Colorectal Cancer

22 Apr 2016

Abstract excerpt

Aberrant DNA methylation is frequently detected in gastrointestinal tumors, and can therefore potentially be used to screen, diagnose, prognosticate, and predict colorectal cancers (CRCs). Although colonoscopic screening remains the gold standard for CRC screening, this procedure is invasive, expensive, and suffers from poor patient compliance. Methylated DNA is an attractive choice for a biomarker substrate...

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PMID: 27102979
DOI: 10.2217/epi-2015-0013

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