Article
Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.
International journal of cancer - 1 Dec 2008
Kim Yong Ho, Kakar Sanjay, Cun Lisa, Deng Guoren, Kim Young S
Abstract excerpt
A subset of colorectal cancers with CpG island methylator phenotype-high (CIMP-H) is frequently associated with MSI and BRAF V600E mutation. Since limited data are available on different histological types of colorectal polyps, we compared the pattern and the frequency of promoter methylation, CI...
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